Two newfangled subject have revealed that mutations in one emplacement can be responsible for several dissimilar , unrelated forms of cancer .
Cancer is not one disease . " Cancer , ” when used ambiguously , refers to the 200 known character of cancer and their subtypes . fundamentally every tissue paper in the human body has the potential of turning cancerous .
It seems intuitive that such a broad smorgasbord of diseases would have an equally full sort of genetic causes . However , after meditate alliteration sequences from across the cancer genome , a common hereditary theme song has been found by scientists at the Memorial Sloane - Kettering Cancer Center in New York . This link has been referred to as the"common genetic needles in an array of genus Cancer hayrick . "
Not only does this work contribute to the overall sympathy of malignant neoplastic disease and provide a unequalled perspective on causing , but the paper itself is one of the first two that will be used inThe Cancer Genome Atlas ( TCGA ) , a collaborative travail that will allow research worker to search and analyze the genomes of Crab , increasing productiveness in inquiry .
TCGA sequences individual tumors , but there also needs to be a taxonomical approach to equate all of the different sample distribution . Josh Stuart , who was not involve with these studies , coordinates a Pan - Cancer Analyses Working Group in TCGA to supervise how neoplasm are tie in to one another . These two studies , which have a combine utilization of 8 , 233 sample of 23 dissimilar type of malignant neoplastic disease , will offer TCGA with much - needed data point which boost the amount of statistical analytic thinking that can occur .
After sequencing 1.5 million loci in the neoplasm genome , the team was able to find 35 venue that scientist have have intercourse cause tumors . More excitingly , they squad found 105 new locations that had previously not been connected with oncogenesis – an awful discovery .
The entropy gain in these survey does n’t only add to our body of knowledge , but can be used to set up the framework for future clinical trials . If researchers well understand how different Crab are related , affected role with different type of cancer may be put into the same test and use the same medication . treat cancer more efficiently on a across-the-board scale would have fantastic implications .
However , even though Cancer the Crab may have the same hereditary origins , they might not respond the same to medicine . While researchers are optimistic , they also recognize that there is a tremendous amount of test necessary to find out for sure .
